MEDICINE 3.0

The future of medicine with personalized, preventive, and precision healthcare powered by advanced bioinformatics and data analytics.

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Technology, BIOMARKERS, LIFESTYLE, MEDICINE 3.0

DAYHOFF TECHNOLOGIES RANKED BEST MICROBIOME TEST

Scientists recognize Dayhoff as most accurate microbiome test using triple-sampling, immediate freezing, and research-grade shotgun metagenomics—setting new industry standard for consumer testing. DALLAS, TX – September 29, 2025 – Dayhoff Technologies, a clinical-grade microbiome testing company, today announced its consumer microbiome test has been recognized by leading microbiome scientists as delivering the most clinically accurate representation of gut microbiome composition among all retail testing options currently available in North America. The peer evaluation, conducted in early 2025 by independent microbiome researchers, compared Dayhoff’s proprietary triple-sampling methodology against single-sample approaches used by competitors of other major consumer testing services. Scientists cited Dayhoff’s unique combination of multiple sampling points, frozen chain-of-custody protocols, and high-depth shotgun metagenomics as setting a new standard for clinical accuracy in direct-to-consumer microbiome analysis. “While other companies rely on single-point sampling that can miss microbial diversity due to temporal variations, our triple-sampling approach captures a comprehensive view of the microbiome ecosystem,” said Roozbeh Ebbadi, CEO of Dayhoff Technologies. “This recognition validates our commitment to bringing research-grade accuracy to consumer health testing.” Revolutionary Triple-Sample Methodology Addresses Industry’s Accuracy Challenge The global microbiome testing market, projected to reach $1.9 billion by 2028 according to Grand View Research¹, has faced persistent challenges with result reliability and clinical utility. Studies published in Nature Microbiology have shown that single-sample tests can vary by up to 50% day-to-day due to natural microbiome fluctuations². Dayhoff’s CLIA-certified testing protocol addresses these limitations through: “The microbiome field has struggled with standardization and reproducibility. Dayhoff’s approach mirrors the protocols we use in clinical research trials,” noted Dr. Armstrong. “The combination of multiple sampling points and frozen preservation is essential for accurate clinical interpretation.” Advanced Computing Platform Accelerates Precision Medicine Applications Dayhoff’s patented analysis platform, originally developed for academic research institutions, processes microbiome data using next-generation GPU acceleration to complete parts of its analysis. This computational infrastructure enables processing speeds up to 10 times faster than traditional methods while maintaining the analytical depth required for clinical applications. The platform’s capabilities have attracted attention from precision medicine researchers studying connections between gut health and chronic conditions including inflammatory bowel disease, metabolic disorders, and mental health conditions. Recent research published in Cell has demonstrated that accurate microbiome profiling can predict treatment responses in up to 60% of IBS patients⁴. Accessibility Meets Clinical Standards Despite its clinical-grade methodology, Dayhoff has maintained consumer accessibility with HSA eligibility for insurance coverage and availability throughout North America. This positions the company uniquely in a market where clinical accuracy often comes at prohibitive costs or requires physician ordering. “We believe everyone deserves access to clinically accurate health information,” added Mr. Ebbadi. “Making our test HSA-eligible removes some financial barriers while maintaining the quality standards healthcare providers expect.” The recognition comes as consumer interest in microbiome testing surges, with Google searches for “gut microbiome test” increasing 250% over the past two years⁵. However, regulatory scrutiny has also intensified, with the FDA issuing guidance on microbiome testing accuracy standards expected in late 2025. About Dayhoff Technologies Founded in 2021 and headquartered in Dallas, Texas, Dayhoff Technologies is pioneering clinical-grade microbiome testing for consumers. The company’s CLIA-certified laboratory and patented analysis platform deliver research-quality microbiome insights directly to consumers, supporting personalized health optimization through precision microbiome analysis. For more information, visit www.dayhoff.ai Forward-Looking Statements This news release contains forward-looking statements and forward-looking information within the meaning of applicable securities laws. The use of any of the words “expect”, “anticipate”, “continue”, “estimate”, “objective”, “may”, “will”, “project”, “should”, “believe”, “plans”, “intends” and similar expressions are intended to identify forward-looking information or statements. The forward-looking statements and information are based on certain key expectations and assumptions made by the Company. Although the Company believes that the expectations and assumptions on which such forward-looking statements and information are based are reasonable, undue reliance should not be placed on the forward-looking statements and information because the Company can give no assurance that they will prove to be correct. References: Media ContactCompany Name: Dayhoff TechnologiesContact Person: InderEmail: Send EmailCountry: United StatesWebsite: https://www.dayhoff.ai/

MEDICINE 3.0

Will AI Replace Doctors? How AI Transforms Healthcare

Key Points: AI in Healthcare: What’s Real vs. Science Fiction When we hear “AI in healthcare,” it’s easy to imagine scenes from sci-fi movies—robots diagnosing patients or replacing human doctors altogether. But in reality, the future of healthcare is likely far more collaborative than catastrophic. Let’s get one thing straight: AI (artificial intelligence) and AGI (artificial general intelligence) are not the same. AI is already integrated into healthcare tools today—supporting diagnostics, predicting health risks, and analyzing data—while AGI, the idea of machines that think and reason like humans, still exists only in theory. How AI Is Already Improving Diagnostics Across World, AI is helping healthcare providers make better, faster decisions—especially in diagnostics. AI algorithms can comb through electronic health records (EHRs), lab results, and imaging data faster than any human could, spotting patterns and red flags that might otherwise go unnoticed. This is especially useful in regions with limited access to specialists, where AI can help triage and prioritize care. For example, AI systems are being trained to identify early signs of disease, such as cancer or cardiovascular risk, from simple blood markers—something that can make proactive care more accessible and effective. Why Doctors Aren’t Going Anywhere AI can process data at lightning speed—but it can’t replace human intuition, empathy, or judgment. Medical care isn’t just about numbers. It’s about understanding a patient’s unique situation, fears, goals, and personal context. The ability to build trust, communicate complex information with compassion, and navigate emotionally charged decisions is something only human doctors can do. That personal connection is often what motivates patients to follow through on care. The Future Is a Team Effort: AI + Doctors Rather than replacing doctors, AI will likely serve as a powerful tool to support them—handling the repetitive, data-heavy tasks and freeing up physicians to do what they do best: care for people. This doctor-AI partnership could lead to: In fact, AI-driven efficiencies are already influencing services like blood testing —making them more accessible, transparent, and personalized. Setting Realistic Expectations for AI AI in healthcare is promising—but it’s not infallible. To embrace it responsibly, we need to set the right expectations: 1. Doctors Make Mistakes Too Medical errors are an unfortunate reality in healthcare—some estimates suggest they’re the third leading cause of death in the U.S. No system is perfect, and AI isn’t being held to replace perfection, but to improve upon the current standard. 2. 100% Accuracy Is Unrealistic Expecting AI to be flawless before implementation sets an impossible bar. If AI can reduce overall error rates, even with occasional mistakes, that’s still a step forward. 3. In Many Cases, AI Performs Better AI tools have shown superior accuracy in certain specialties. For example, AI has outperformed radiologists in identifying breast cancer in mammograms in some clinical studies. 4. It’s About Risk-Benefit Balance AI isn’t perfect—but if it’s consistently more accurate or faster than human analysis in specific areas, its benefits can outweigh its risks. 5. AI Learns—and Fast Unlike human clinicians, AI systems can learn from every case they process. With continued real-world data, their performance improves rapidly. Early implementation means faster evolution. The Bottom Line: AI Won’t Replace Doctors, But It Will Reinvent Healthcare AI isn’t here to push doctors out of their jobs—it’s here to make healthcare smarter, faster, and more personalized. For patients, that means better outcomes, shorter wait times, and more control over their health. At DAYHOFF, we’re embracing this future with open arms. Our at-home blood testing and health analysis platform uses smart technology to deliver insights you can act on. But we never forget the human element. Your results are interpreted by experts, and we’re with you every step of the way. The DAYHOFF Advantage: AI Meets Human Care DAYHOFF is one of the few health companies offering: We’re not just giving you data—we’re helping you understand what it means, and how to use it to live better. Ready to experience AI-powered, human-centered healthcare? Explore DAYHOFF’s plans today and take control of your health—with the best of both worlds.

MEDICINE 3.0

Medicine 2.0 vs Medicine 3.0

How Healthcare Is Evolving—And Why It Matters Key Takeaways The Evolution of Healthcare Modern medicine is undergoing a revolution. Thanks to scientific innovation and technology, we’re moving beyond treating diseases after they strike and toward preventing them before they begin. This evolution reflects a deeper understanding of how genetics, environment, and lifestyle intersect to shape our health. Proactive care isn’t just about living longer—it’s about living better. By focusing on early detection and personalized plans, healthcare can now work for you, not just on you. It’s a smarter, more efficient, and more equitable future of care. Medicine 2.0: Reactive, But Necessary Medicine 2.0—the reactive model—has formed the backbone of healthcare system. It works like this: This model helps prioritize urgent care needs in a universal system. But it’s not without flaws: With an aging population and rising chronic diseases, System is under pressure—and reactive care alone can’t keep up. Medicine 3.0: The Proactive Revolution Welcome to Medicine 3.0, a forward-thinking model rooted in prevention, personalization, and performance. It’s about owning your health journey. Here’s what it looks like: As Dr. Peter Attia puts it: “The best time to treat a disease is before it happens.” Medicine 2.0 vs Medicine 3.0: A Comparison Feature Medicine 2.0 Medicine 3.0 Approach Reactive Proactive Trigger Symptoms appear Risk factors + early detection Tools Diagnosis + treatment Biomarkers, genetics, wearables Goal Treat disease Prevent and optimize health Access Universal, but slow Personalized, often premium These models aren’t at odds—they’re complementary. Emergency care is still vital. But proactive care can reduce long-term strain, costs, and suffering. The Future of Healthcare More patients are seeking proactive care through personalized clinics and wellness platforms. While this often means paying out of pocket, many see it as an investment in a longer, healthier life. Doesn’t need to choose between the old and the new—it needs both. By blending reactive and proactive care, we can relieve system strain, enhance longevity, and empower individuals. Take Control with DAYHOFF Ready to shift from reactive to proactive care? DAYHOFF makes it easier than ever to begin your Medicine 3.0 journey. DAYHOFF is redefining proactive health —convenient, science-backed, and fully personalized. Start your journey with DAYHOFF. Your future self will thank you.

MEDICINE 3.0

Why Men Avoid the Doctor – And How We Can Change That

Many men continue to skip routine check-ups and avoid seeking medical care until symptoms become too serious to ignore. While this might seem like harmless procrastination, the long-term consequences are anything but. At DAYHOFF, we’re tackling this issue head-on by offering smarter, more convenient solutions that make preventative healthcare more accessible, especially for men. Let’s break down why men avoid the doctor—and how technology like biomarker testing is redefining what it means to take care of your health. Key Insights: The Stats Paint a Clear Picture Data shows a persistent gap in healthcare engagement between men and women: This trend has serious implications—not just for men’s health, but for their families, communities, and the healthcare system overall. Why Do Men Avoid Preventive Healthcare? Several cultural and systemic factors play into this hesitation: Independence Many men equate health issues with weakness or loss of control. Seeking help feels unnecessary unless something is clearly wrong. Fear of Diagnosis There’s a strong “what I don’t know won’t hurt me” mentality. But delaying diagnosis often makes things worse—not better. Time Constraints Between work, family, and life responsibilities, healthcare drops to the bottom of the to-do list. Lack of Awareness Many men don’t know what screenings they should be doing—or when. Preventive care isn’t talked about nearly enough. System Friction Long wait times, limited access to doctors, and confusing healthcare navigation make appointments feel more like a hassle than a help. What’s at Risk When Men Delay Care? Avoiding routine check-ups means missing the chance to catch issues early—when they’re easiest to treat. The consequences include: Prevention isn’t just about avoiding illness—it’s about optimizing energy, longevity, and resilience. Enter Biomarker Testing: A Smarter Approach to Men’s Health At DAYHOFF, we’re helping to close the gap by offering precision biomarker testing—a modern alternative that fits into your lifestyle. Here’s why this matters: Convenience Test from home or at a nearby clinic—no waiting rooms, no unnecessary appointments. Privacy Avoid awkward conversations or unnecessary tests. Track your health discreetly, with full control. Data-Driven Receive a comprehensive, science-backed report based on over 50 key health biomarkers—including heart, hormone, and metabolic health. Early Detection Catch warning signs before they become full-blown issues. Personalized Action Plan No guesswork. Your results come with step-by-step recommendations tailored to your body and goals. How to Start Taking Control of Your Health Whether you’re looking to get ahead of chronic conditions or just want to understand your body better, here’s how to get started: Small steps today lead to major gains tomorrow. You don’t have to overhaul your life—you just have to start the journey. Changing the Narrative Around Men’s Health Improving men’s health isn’t just about individual choices—it’s about shifting the way we approach preventive care. At DAYHOFF, we’re building tools that make staying on top of your health easy, efficient, and empowering. No lectures. No waiting rooms. Just science, simplicity, and better outcomes. Why Patients Trust DAYHOFF? DAYHOFF is one of only health optimization platforms offering: We bridge the gap between reactive care and proactive health optimization—so you can stay ahead of problems instead of responding to them. Your Health, Your Call Let’s face it—life’s too short to wait for something to go wrong. With tools like biomarker testing, you can stay informed, stay ahead, and stay in control. DAYHOFF: Precision Health for the Modern ManWhere data meets action—because real strength starts with knowing your numbers.

Dayhoff does not diagnose, treat, or prevent diseases. All tests and analyses are for informational purposes only and should be reviewed with a licensed medical professional where applicable.

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