Your microbiome has 38 trillion reasons to matter

What is a microbiome?

Your microbiome is home to 38 trillion microbes that are vital to your immune system and overall health.
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At Birth

As a baby is born, the mother transfers essential microbes that becomes the baby’s first microbial colonizers. These tiny organisms lay the foundation for the baby’s immune system and long term health.

Key factors during pregnancy that shape this early microbiome transfer:

After Birth

Breastfeeding continues the transfer of beneficial bacteria from mother to baby. Human Milk Oligosaccharides (HMOs) in breastmilk nourish the friendly bacteria inherited at birth, helping them grow rapidly and crowd out harmful microbes.

In the first year, a baby’s gut is especially influenced by:

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Ages 1 – 3: Toddler Years

By the age of three, a child’s gut microbiome begins to resemble that of an adult. During toddlerhood, environmental exposures play a major role in diversifying their gut bacteria—everything from playing in soil to interacting with pets supports a healthier microbiome.

Additional influences on the toddler microbiome include:

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of children in the U.S. live with at least one chronic health condition—and that number continues to rise.

How do we look at the microbiome?

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High-Resolution Analysis

We leverage deep shotgun metagenomic sequencing—the gold standard in microbiome science—for a detailed and dependable analysis that empowers confident, informed decisions.

Breakthrough Insights

Our functional profiling reveals not just which microbes are present and in what quantities, but also what roles they’re playing in your body.

Targeted Recommendations

Using strain-level precision, we identify specific microbes, track their transfer, assess probiotic impact, and deliver science-backed, personalized suggestions.

Created in collaboration with leading experts in early-life microbiome health

Dr. David Song, MD

Chief Medical Officer
Integrative Pediatrician and Pediatric
Functional Medicine Expert
Founder, Healthy Kids Happy Kids

Dr. David Song, MD

Chief Medical Officer
Integrative Pediatrician and Pediatric
Functional Medicine Expert
Founder, Healthy Kids Happy Kids

Dr. David Song, MD

Chief Medical Officer
Integrative Pediatrician and Pediatric
Functional Medicine Expert
Founder, Healthy Kids Happy Kids

Dr. David Song, MD

Chief Medical Officer
Integrative Pediatrician and Pediatric
Functional Medicine Expert
Founder, Healthy Kids Happy Kids

Dr. David Song, MD

Chief Medical Officer
Integrative Pediatrician and Pediatric
Functional Medicine Expert
Founder, Healthy Kids Happy Kids

Dr. David Song, MD

Chief Medical Officer
Integrative Pediatrician and Pediatric
Functional Medicine Expert
Founder, Healthy Kids Happy Kids

“Imagine a world where you will take your baby to a health care check. They will routinely monitor the gut microbiome development….

If any disruptions are noted, a tailor-made product to restore the gut microbiota will be prescribed. The onset of any chronic diseases will be extremely rare.”

Dr. Henna Maria Uusitupa

Microbiome Researcher, TED Speaker (2.5M views)

The first 1,000 days are the most critical for shaping your baby’s gut and lifelong health.

“If you upset this process in early life then we may have consequences later and that can lead to production of disease later in life.”

Rodney Dietert, PhD

Professor Emeritus of Microbiology
& Immunology, Cornell University

See how Dayhoff’s insights have helped families thrive.

Dayhoff Case Study: What 30 Days of Junk Food Did to Alex’s Gut

Dayhoff Case Study: How One Family Resolved Eczema and Eased OCD Symptoms

Dayhoff Case Study: A Mom Uses Gut Health to Fight Her Child’s Eczema

Dayhoff Case Study: A Holistic Path to Soothing Eczema Flares

Comprehensive care, starting with your microbiome

Actionable Support

From preconception to adulthood, we guide your family’s health every step of the way with clear, practical insights.

Personalized Guidance

Our medically reviewed recommendations are tailored to your unique test results—for care that’s truly made for you.

Science-Driven

We nerd out on the latest research so you don’t have to—bringing you trusted, evidence-based insights you can rely on.

We're advancing microbiome research and gut health testing for the whole family.

Our team is actively conducting research to deepen the understanding of the microbiome and its connection to chronic conditions. This includes leading our own clinical studies and publishing peer-reviewed findings to drive meaningful progress in personalized health.
How the early-life gut microbiome shapes childhood health and long-term chronic conditions

Explore the research for yourself

These key studies delve deeper into the complex world of microbiome health.
Stunted microbiota and opportunistic pathogen colonisation in caesarean section birth
Researchers studied 576 full-term infants and their mothers, finding that delivery mode strongly influences gut microbiota composition during the first month and continues shaping the infant microbiome through the first year.
General Studies
Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma
Delivery mode and associated changes in gut microbiota have been linked to a higher risk of developing childhood asthma, highlighting the long-term health impact of early microbial exposure.
Allergies & Eczema
Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.
Researchers identified bacterial strains and genes passed from mothers to newborns at birth, confirming the transmission of beneficial microbes and underscoring the critical role of vertical microbial inheritance.
General Studies
Healthy infants harbor intestinal bacteria that protect against food allergy
Researchers transplanted gut bacteria from healthy and milk-allergic infants into germ-free mice. Mice with microbes from healthy infants were protected from allergic reactions, highlighting gut bacteria’s role in preventing food allergies.
Allergies & Eczema
Early infancy microbial and metabolic alterations affect risk of childhood asthma
Researchers discovered four key bacteria present at 3 months of age that significantly reduce the risk of developing asthma, suggesting these microbes may have a protective role in early immune development.
Allergies & Eczema
Type 1 & Type 2 Diabetes
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study
Analyzing nearly 11,000 stool samples from 783 children, researchers found that infants without Type 1 diabetes had more microbial genes for fermentation and short-chain fatty acid production—key to gut and immune health.
Type 1 & Type 2 Diabetes
Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation
Researchers found that a newborn’s gut microbiome directly shapes immune development. Low levels of beneficial bacteria disrupted T cell balance, increasing the risk of childhood allergic asthma.
General Studies
Roles of Birth Mode and Infant Gut Microbiota in Intergenerational Transmission of Overweight and Obesity From Mother to Offspring
In a study of 935 mother-infant pairs, infants of mothers with overweight or obesity—and those delivered by C-section—had significantly higher odds of being overweight at ages 1 and 3.
Obesity
Intestinal microbiota in infants at high risk for allergy: Effects of prebiotics and role in eczema development
Hydrolyzed protein formula with added prebiotics may reshape the gut microbiome in high-risk infants, supporting microbial development similar to breastfed babies and potentially reducing future allergy risk.
General Studies
Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice
Infants born to mothers with IBD showed an unhealthy gut microbiome lacking Bifidobacteria. In germ-free mice, this altered microbiome disrupted gut immunity, suggesting early microbiome-based interventions may reduce future IBD risk.
Obesity
Temporal development of the gut microbiome in early childhood from the TEDDY study
Using TEDDY study data, researchers found breastfeeding was the strongest influence on infant microbiome composition from 3–14 months, promoting Bifidobacterium growth. Microbiome diversity increased after weaning with expanded diets.
Type 1 & Type 2 Diabetes
Sports Medicine
The Athlete Gut Microbiome and its Relevance to Health and Performance: A Review
The gut microbiome influences health and may interact bidirectionally with exercise. This review explores its potential to enhance athletic performance through microbiome manipulation, offering promise for elite athletes.
General Studies

Science-Backed Insights from the Dayhoff Team

Stay informed on the latest microbiome research and discoveries—explore expert articles on the Dayhoff blog.

Have Questions? We’ve Got Answers

Dayhoff does not diagnose, treat, or prevent diseases. All tests and analyses are for informational purposes only and should be reviewed with a licensed medical professional where applicable.

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